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  1. 首頁 > 生化試劑 > 多肽 > 多肽藥物遞送 > Somatostatin-14

Somatostatin-14

    
98.1%

Somatostatin-14

源葉(MedMol)
S80693 一鍵復制產(chǎn)品信息
38916-34-6
C76H104N18O19S2
1637.88
MFCD00076762
生長抑素 14
貨號 規(guī)格 價格 上海 北京 武漢 南京 購買數(shù)量
S80693-20mg
 98.1% ￥300.00 3 - - -
S80693-100mg
 98.1% ￥1200.00 2 - - -
產(chǎn)品介紹 參考文獻 質(zhì)檢證書(COA) 摩爾濃度計算器 相關產(chǎn)品

產(chǎn)品介紹

Cyclic somatostatin (SRIF-14) is a growth hormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers. Cyclic somatostatin is a neuropeptide co-stored with acetylcholine in the cardiac parasympathetic innervation, exerts influences directly on contraction of ventricular cardiomyocytes. Cyclic somatostatin inhibits the contractile response of isoprenaline with an IC50 value of 13 nM. Cyclic somatostatin can be used for the research of cardiovascular disease

產(chǎn)品描述： Cyclic somatostatin (SRIF-14) is a growth hormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers. Cyclic somatostatin is a neuropeptide co-stored with acetylcholine in the cardiac parasympathetic innervation, exerts influences directly on contraction of ventricular cardiomyocytes. Cyclic somatostatin inhibits the contractile response of isoprenaline with an IC50 value of 13 nM. Cyclic somatostatin can be used for the research of cardiovascular disease
靶點： IC50: 13 nM (contractile response of isoprenaline)
體內(nèi)研究： Cyclic somatostatin (5 μg/kg; i.v. per hour once for 18-22 hours) affects visceral metabolism in ruminants
參考文獻： 1. Murray F, et al. Positive and negative contractile effects of somatostatin-14 on rat ventricular cardiomyocytes. J Cardiovasc Pharmacol. 2001 Mar;37(3):324-32. 2. Bell D, et al. SRIF receptor subtype expression and involvement in positive and negative contractile effects of somatostatin-14 (SRIF-14) in ventricular cardiomyocytes. Cell Physiol Biochem. 2008;22(5-6):653-64. 3. https://pubmed.ncbi.nlm.nih.gov/9374319/
溶解性： H2O  :  100  mg/mL  (61.05  mM;  Need  ultrasonic)    DMF  :  100  mg/mL  (61.05  mM;  Need  ultrasonic)
保存條件： -20℃
配置溶液濃度參考：
1mg 5mg 10mg
1 mM 0.611 ml 3.053 ml 6.105 ml
5 mM 0.122 ml 0.611 ml 1.221 ml
10 mM 0.061 ml 0.305 ml 0.611 ml
50 mM 0.012 ml 0.061 ml 0.122 ml
注意： 部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

質(zhì)檢證書(COA)

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批號：JS298415 貨號：S20001-25g
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摩爾濃度計算器

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