58. [IF=5.7] Zuguo Liang et al."Protective effect of ginseng extract and total ginsenosides on hematopoietic stem cell damage by inhibiting cell apoptosis and regulating the intestinal microflora."INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE.2025 Jan;55(1):1-18 57. [IF=6.2] Jingjing Li et al."Mechanism of podophyllotoxin-induced ovarian toxicity via the AMPK/TSC1/mTOR/ULK1 axis in rats on the basis of toxicological evidence chain (TEC) concept."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.2025 Jan;290:117617 56. [IF=2.9] Yushuang Xing et al."Inotodiol induces hepatocellular carcinoma apoptosis by activation of MAPK/ERK pathway."PLoS One.2025 Jan;20(1):e0318450 55. [IF=3.2] Junqi Zhang et al."Analysis of the bioactive parts and components of Aralia elata (Miq.) Seem based on non-targeted metabolomics and its hepatoprotective effects induced by cyclophosphamide."JOURNAL OF FOOD SCIENCE.2025 Feb;90(2):e70057 54. [IF=7] Yuhang Hao et al."Nondigestible stachyose alleviates cyclophosphamide-induced small intestinal mucosal injury in mice by regulating intestinal exosomal miRNAs, independently of the gut microbiota."FOOD RESEARCH INTERNATIONAL.2025 Mar;:116258 53. [IF=3.7] Yuejuan Fang et al."Puerarin Ameliorates Premature Ovarian Failure by Activation of Mitochondrial Biogenesis, Dynamics, and Mitophagy Through Up-Regulation of SIRT1."Advanced Therapeutics.2025 Mar;:2400310 52. [IF=4.8] Shuanghui Shi et al."Structural characterization of raw and wine-steamed Polygonatum cyrtonema Hua oligosaccharides and their bioactivity on immune regulation via modifying the gut microbiota."INTERNATIONAL IMMUNOPHARMACOLOGY.2025 Apr;153:114468 51. [IF=4.4] Qu Minmin et al."Assessing genotoxic effects of chemotherapy agents by a robust in vitro assay based on mass spectrometric quantification of γ-H2AX in HepG2 cells."Frontiers in Pharmacology.2024 Jun;15: 50. [IF=5.7] Xuejiao Wang et al."A Hirsutella sinensis Alcohol Extract Exerts Bidirectional Immunoregulatory Effects by Regulating Macrophage Polarization."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2024;XXXX(XXX):XXX-XXX 49. [IF=4.3] Qinbing Xue et al."Lycorine (Lycoris radiata)—a unique natural medicine on breast cancer."JOURNAL OF CELLULAR AND MOLECULAR MEDICINE.2024 Aug;28(16):e70032 48. [IF=2.9] Yuhao Meng et al."Therapeutic effects of curculigoside on cyclophosphamide-induced premature ovarian failure in mice."CLIMACTERIC. 47. [IF=8.2] Qinbing Xue et al."Structural characterization and immune-enhancing effects of a novel polysaccharide extracted from Sargassum fusiforme."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES".2024 May;:132497 46. [IF=1.8] Ruxin Wang et al."Network Pharmacology and In Vivo Validation to Explore the Potential Active Ingredients and Mechanisms of Ziyin Buyang Formula in Diminished Ovarian Reserve."Natural Product Communications.10.1177/1934578X241242281 45. [IF=6.3] Ping Tang et al."Ameliorative effect of total ginsenosides from heat-treated fresh ginseng against cyclophosphamide-induced liver injury in mice."Current Research in Food Science".2024 Jan;8:100734 44. [IF=6.6] Qiao Qinggang et al."Structure and immunostimulating activity of polysaccharides derived from the roots and leaves of dandelion."Chemical and Biological Technologies in Agriculture".2024 Dec;11(1):1-18 43. [IF=5.2] Zheng Mei et al."Synergistic effects of ceftazidime/avibactam combined with meropenem in a murine model of infection with KPC-producing Klebsiella pneumoniae."JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY".2024 Mar;: 42. [IF=2] Weimei Zhou et al."LIPUS combined with TFSC alleviates premature ovarian failure by promoting autophagy and inhibiting apoptosis."GYNECOLOGICAL ENDOCRINOLOGY.2023;39(1):Article: 2258422 41. [IF=4.6] Yi Cheng et al."Effects of Solid Fermentation on Polygonatum cyrtonema Polysaccharides: Isolation, Characterization and Bioactivities."MOLECULES.2023 Jan;28(14):5498 40. [IF=2.7] Xiaoyin Meng et al."Hydrogen-rich water treatment targets RT1-Db1 and RT1-Bb to alleviate premature ovarian failure in rats."PeerJ.2023 Jun;11:e15564 39. [IF=6.4] Zhang Hongyin et al."Immunomodulatory activity of semen Ziziphi Spinosae protein: a potential plant protein functional food raw material."npj Science of Food.2023 Jun;7(1):1-13 38. [IF=3.318] Peng Qi et al."Simultaneous quantification of pirarubicin, doxorubicin, cyclophosphamide, and vincristine in human plasma of patients with non-Hodgkin's lymphoma by LC–MS/MS method."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND 37. [IF=9.043] Yi Zhang et al."Flufenamic Acid, a Promising Agent for the Sensitization of Colistin-Resistant Gram-Negative Bacteria to Colistin."Microbiology Spectrum. 36. [IF=11.504] Zhengxin Shan et al."Insight into the structural and immunomodulatory relationships of polysaccharides from Dendrobium officinale-an in vivo study."FOOD HYDROCOLLOIDS.2023 May;139:108560 35. [IF=4.014] Min He et al."Effect of Rubia cordifolia L. processed Terminalia chebula Retz polysaccharide on the histological structure and apoptosis in the spleen in immunosuppressed Chinese yellow quail."POULTRY SCIENCE.2022 Dec;:102416 34. [IF=4.219] Yiqun Li et al."Emodin-8-O-β-D-glucopyranoside, a natural hydroxyanthraquinone glycoside from plant, suppresses cancer cell proliferation via p21-CDKs-Rb axis."Toxicol Appl Pharm. 2022 Mar;438:115909 33. [IF=2.863] Jian Zhang et al."Immunomodulatory effects of selenium-enriched peptides from soybean in cyclophosphamide-induced immunosuppressed mice."Food Sci Nutr. 2021 Nov;9(11):6322-6334 32. [IF=4.411] Feng Liu et al."Immunomodulatory Activity of Carboxymethyl Pachymaran on Immunosuppressed Mice Induced by Cyclophosphamide."Molecules. 2021 Jan;26(19):5733 31. [IF=5.64] Yan Yong et al."Exogenous Citrulline and Glutamine Contribute to Reverse the Resistance of Salmonella to Apramycin."Front Microbiol. 2021; 12: 759170 30. [IF=7.514] Tingting Ma et al."Effects of co-fermented collagen peptide-jackfruit juice on the immune response and gut microbiota in immunosuppressed mice."Food Chem. 2021 Dec;365:130487 29. [IF=9.229] Sheng Xu et al."Fabrication of a Silk Sericin Hydrogel System Delivering Human Lactoferrin Using Genetically Engineered Silk with Improved Bioavailability to Alleviate Chemotherapy-Induced Immunosuppression."Acs Appl Mater Inter. 2021;13(38):45175–45190 28. [IF=4.759] Li Zhou et al."Independent or integrative processing approach of metabolite datasets from different biospecimens potentially affects metabolic pathway recognition in metabolomics."J Chromatogr A. 2019 Feb;1587:146 27. [IF=5.79] Yu Yang et al."Novel partners with colistin to increase its in vivo therapeutic effectiveness and prevent the occurrence of colistin resistance in NDM- and MCR-co-producing Escherichia coli in a murine infection model."J Antimicrob Chemoth. 2019 Jan;74(1) 26. 牛佳卉,袁靜,魏然,張曉富,張慧芳,賈金玉,趙文.紅棗多糖對小鼠腸道免疫屏障的保護(hù)作用及機(jī)制研究[J].食品工業(yè)科技,2021,42(04):295-300+306. 25. 張林,章亮,肖圣雄,姚飛虹,張輝.釹水楊酸硫代脯氨酸配合物對小鼠的LD_(50)和骨髓細(xì)胞微核實驗研究[J].廣東化工,2020,47(16):63-64. 24. 艾丹,常若葵,張斌,于瑋瑋,王遠(yuǎn)宏.美極梅奇酵母T-2灌胃對小鼠的毒性作用[J].食品研究與開發(fā),2020,41(22):1-6. 23. 王丹陽,朱曉慶,谷新利,王蒙蒙,孫國結(jié),武夢麗,王虹,丁艷,羅燕,連科迅.硒化甘草多糖聯(lián)合抗生素體外抑菌作用及體內(nèi)免疫調(diào)節(jié)作用研究[J].中國獸醫(yī)科學(xué),2021,51(01):126-134. 22. 羅亮,李欣蔓,馬靖宜,林居純,符華林,顧健,何黎黎,袁志翔.白蘆筍鮮汁及殘渣醇提物不同極性部位的免疫活性研究[J].中南藥學(xué),2021,19(03):397-401. 21. 李莉,劉瀟祎,蘇劉艷,蔣昕,張祎,王睿睿.屏邊三七提取物協(xié)同氟康唑抗耐藥白念珠菌的作用及機(jī)制研究[J].中華中醫(yī)藥學(xué)刊,2021,39(01):51-57+269-273. 20. 李瑩雪,王銳銀,包永明.芹菜素與丹參酮Ⅱ_A的協(xié)同抗腫瘤作用及機(jī)制[J].中草藥,2020,51(22):5788-5797. 19. 何巧梅,於芳芳,孫希,丁曉丹,袁秀杰,張巖,宋獻(xiàn)民.異基因骨髓移植混合嵌合體小鼠模型的構(gòu)建及影響因素分析[J].中國實驗血液學(xué)雜志,2021,29(02):603-609. 18. 馬曉平, 楊秋霞, 俞演,等. 大熊貓源枝孢樣枝孢霉野生株(Z20)與突變株(Zt)部分生物學(xué)特性及藥敏試驗比較[J]. 浙江農(nóng)業(yè)學(xué)報, 2018(8):1328-1335. 17. 伍璀 牛瑞斌 葉楓 等. 丙泊酚下調(diào)miR-93-5p表達(dá)對乳腺癌MDA-MB-231細(xì)胞增殖 侵襲的影響[J]. 中國藥師 2020 v.23(06):48-53. 16. 郝李娟, 李瑞娟, 習(xí)南,等. 黃芪多糖對血虛模型雞外周血的影響[J]. 中國畜牧獸醫(yī), 2014, 41(4):255-257. 15. 盧燕, 李亞菲, 肖倩雯,等. 馬波沙星在多殺性巴氏桿菌感染的小鼠體內(nèi)的藥動學(xué)研究[J]. 中國獸醫(yī)科學(xué), 2016(9):1183-1188. 14. 李曉, 高慧婕, 朱桐林,等. 阿膠對環(huán)磷酰胺所致免疫抑制小鼠的免疫保護(hù)作用[J]. 濟(jì)寧醫(yī)學(xué)院學(xué)報, 2019, 42(6):385-389. 13. 施強(qiáng), 鄭勇斌, 睢鳳英,等. 尼古丁對小鼠骨髓細(xì)胞微核影響的實驗研究[J]. 中國美容醫(yī)學(xué)雜志, 2011, 20(0z6):118,120. 12. 陳麗娥, 孫盛, 俞赟霞,等. 西北傳統(tǒng)食品中乳酸菌的分離及提高免疫力菌株的篩選[J]. 中國乳品工業(yè), 2019(10). 11. 胡嘉宇, 常若葵, 劉柏君,等. 葡萄球菌S-35對小鼠的毒性作用[J]. 農(nóng)藥, 2020, v.59(05):38-42. 10. 王建舫, 賈夢然, 胡艷姣,等. 芪參口服液對免疫功能低下小鼠的保護(hù)作用[J]. 中國農(nóng)學(xué)通報, 2013(11):24-28. 9. 李培寧,江漪,陳秀娟,劉香梅,龐增雄,黃宇鋒.致畸試驗中3種常用陽性對照物的效果比較[J].癌變·畸變·突變,2017,29(03):235-240. 8. 陳秀娟,江漪,李敏,李培寧,孫俠,陳梓靈,丘智峰,黃宇鋒.用吖啶橙-流式細(xì)胞儀技術(shù)檢測間苯二胺、對苯二胺誘導(dǎo)的小鼠骨髓細(xì)胞微核率[J].實驗動物與比較醫(yī)學(xué),2019,39(03):231-235. 7. 陳龍云, 周艷艷, 徐安莉,等. 槲皮苷對免疫功能低下小鼠的免疫調(diào)節(jié)作用[J]. 中國免疫學(xué)雜志, 2019(19). 6. 張維彬, 樊丹采, 張敏,等. 桔梗水提液及其主要成分桔梗皂苷D對環(huán)磷酰胺藥代動力學(xué)的影響[J]. 中藥材, 2016, 39(011):2633-2635. 5. 劉漢斌, 2], 彭嬌嬌,等. 強(qiáng)雞散對免疫抑制小鼠脾轉(zhuǎn)錄因子GATA-3和T-bet表達(dá)量的影響[J]. 廣東農(nóng)業(yè)科學(xué), 2014(19). 4. 曹洛云, 李天嬌, 孟憲生,等. 山豆根生物堿對DEN誘發(fā)肝癌大鼠的作用及機(jī)制研究[J]. 中國現(xiàn)代應(yīng)用藥學(xué), 2018, 035(003):370-374. 3. 李淑艷, 王玉華, 吳東興,等. 大鼠急性腸炎模型制備方法的建立與探討[J]. 中成藥, 2018, 40(002):444-446. 2. 周小露, 陳崇俊, 冉莉莎,等. 復(fù)合茯磚袋泡茶的配方優(yōu)化及安全性評價[J]. 現(xiàn)代食品科技, 2020, v.36;No.248(04):216-225. 1. 聶露霞,廖水亨,苑述剛,馬少丹.基于免疫力低下模型小鼠的樟芝升白湯肝腎毒性研究[J].中醫(yī)臨床研究,2016,8(23):8-11.